MOTS-C

About This Compound

The Science Behind MOTS-C

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a novel peptide encoded within the mitochondrial genome, placing it in a unique class of mitochondria-derived peptides (MDPs). It has emerged as a significant regulator of systemic metabolic homeostasis.

MOTS-C activates the AMPK pathway, a master regulator of cellular energy sensing. Under metabolic stress, MOTS-C translocates from the mitochondria to the nucleus, where it regulates the expression of antioxidant response element (ARE)-driven genes. This action enhances insulin sensitivity and reduces lipid accumulation in skeletal muscle.

Research Highlights

Key Findings & Mechanisms

The following findings are drawn from peer-reviewed preclinical and clinical research. All compounds supplied by Maxx Labs are intended for qualified research use only and are not approved for human therapeutic use.

Demonstrated reversal of diet-induced insulin resistance in mouse models
Shown to improve exercise capacity and muscle function in aged animal studies
Research indicates MOTS-C levels decline with age, correlating with metabolic dysfunction
Investigated for potential roles in longevity pathways alongside other mitochondria-derived signals

Product Specifications

Quality Standards

Purity ≥99.0% Verified by third-party HPLC analysis

Form Lyophilized Sterile lyophilized powder sealed under inert gas

Storage 36–46°F Stable for 24 months when stored properly

Synthesis USA Manufactured cGMP-compliant facility with full chain of custody

Certificate of Analysis Available

Every batch of MOTS-C from Maxx Labs undergoes independent third-party testing for identity, purity, and sterility. Request the COA for your specific lot number directly from our team.

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The Science Behind MOTS-C

Key Findings & Mechanisms

Quality Standards

Certificate of Analysis Available

Related Compounds

NAD+

IGF-1 LR3

Ipamorelin