Long R3 Insulin-like Growth Factor 1
About This Compound
IGF-1 LR3 is a recombinant analog of human IGF-1 in which the glutamic acid at position 3 is replaced by arginine and a 13 amino acid extension is added to the N-terminus. These modifications significantly enhance its potency and half-life relative to native IGF-1.
IGF-1 LR3 binds to IGF-1 receptors (IGF1R) on target cells with high affinity but has substantially reduced binding to IGF-binding proteins (IGFBPs) compared to native IGF-1. This results in a longer systemic half-life and greater bioavailability at target tissues. It activates the PI3K/Akt/mTOR pathway, promoting protein synthesis, cellular proliferation, and inhibition of apoptosis.
Research Highlights
The following findings are drawn from peer-reviewed preclinical and clinical research. All compounds supplied by Maxx Labs are intended for qualified research use only and are not approved for human therapeutic use.
Product Specifications
Every batch of IGF-1 LR3 from Maxx Labs undergoes independent third-party testing for identity, purity, and sterility. Request the COA for your specific lot number directly from our team.